Link to Prion Alliance blog: ‘All of the things’
Link: All of the things From: prionalliance.org
Link to blog: We have an open IND. What comes next?
Link: We have an open IND. What comes next? From: cureffi.org
Link to post: ION717 trial fully enrolled
Link: ION717 Trial fully Enrolled from: cureFFI.org
Clinical Trial Update for Prion Diseases, December 2024
December 2024 December 30th, 2024 - Enrolment is now complete for the Ionis Phase 1/2a clinical trial of ION717 called PrProfile for symptomatic prion disease patients. Updates will be provided as…
Link to article (update from Prion Alliance): Divalent siRNA for prion disease
Link: Divalent siRNA for prion disease Update from Prion Alliancevia biorxiv.org
Link to article: Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor
Link: Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor from science.org
Link to article: ‘Epigenome editor’ silences gene that causes deadly brain disorders
Link: ‘Epigenome editor’ silences gene that causes deadly brain disorders by Gemma Conroy from nature.com
About Gate Bioscience
Gate Bioscience is creating a new category of medicines called Molecular Gates. Our therapeutics are small molecules that selectively eliminate harmful extracellular proteins at their origin, inside the cell. We…
Link to blog: Why the ION717 trial is paused
Below is a link to Erik Minikel's blog sharing his perspective on the Ionis Community Statement regarding the recruiting pause of the Prion Disease clinical trial. Link - Why the ION717…
Link to article – Maximising Impact: Professor Andy Hill’s Journey
From Cosmos Studio https://cosmosmagazine.com/cosmos-studio/andy-hill-applied-research-impact-medicinal-science-journey