Video presentation: “Small Molecules to eliminate Prion protein”- Nina Oberbeck
Nina Oberbeck from Gate Bioscience at the 2023 CJD Conference, Melbourne Australia. https://youtu.be/G-MSuthL2W8
Link to blog: Prion Alliance – First details of Ionis trial disclosed
Post by Eric Minikel from Prion Alliance Link - First details of Ionis trial disclosed
Understanding Clinical Trials
Please find below links to some general information on clinical trials which may be helpful in the lead-up to the commencement of clinical trials for prion disease: U.S. Department of…
Link to Article: Concordance of CSF RT-QuIC across the European Creutzfeldt-Jakob Disease surveillance network
Link: Concordance of CSF RT-QuIC across the European Creutzfeldt-Jakob Disease surveillance network from Doc Wire News. Article originally published National Library Medicine
Article: Early Diagnosis of V180I Genetic Creutzfeldt-Jakob Disease at the Preserved Cognitive Function Stage
Early Diagnosis of V180I Genetic Creutzfeldt-Jakob Disease at the Preserved Cognitive Function Stage from Cureus Journal of Medical Science
Podcast: In conversation with… John Collinge
John Collinge (MRC Prion Unit, University College London, London, UK) discusses a first-in-human treatment programme to give PRN100, an anti-prion-protein monoclonal antibody, to patients with Creutzfeldt–Jakob disease; the report is published in…
Article: Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt–Jakob disease: evaluation of a first-in-human treatment programme
TLN_April2022_p342_354 (pdf) The Lancet Neurology April2022 p342_354 (online) from The Lancet Neurology